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Brain scan study aims to sharpen diagnosis of neurological diseases

NCT ID NCT02455284

Knowledge-focused Sponsor: University Hospital, Tours Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a special MRI technique called tractography can accurately map the brain's white matter tracts, which are like highways for nerve signals. Researchers scanned 134 older adults and compared the MRI images to brain tissue samples. The goal is to validate this non-invasive method for better diagnosis of neurological conditions.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors better diagnose and monitor brain diseases by improving MRI-based brain mapping.
What could go wrong
This is an early validation study, not a treatment trial. Results may not directly improve patient care, and the technique may not work as well in real-world settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

134 people

The number who actually took part.

Start date

Oct 2015

Finished

Feb 2021

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

82 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Prior enrollment in a body donation program * Age ≥ 82 years * Absence of major cognitive impairment as demonstrated by independent living skills in 4 fields evaluated by the IADL (4 items) (Lawton and Brody, 1969) * Distance to one of the participating laboratories ≤ 120km * Able to remain supine in the MR scanner for acquisition duration (60 min), * Affiliation to Social Security * Informed and written consent Non Inclusion Criteria: * Past or present Neurological or Neurosurgical diseases (excluding trauma or degenerative spinal lesions) * Uncontrolled: High blood pressure, diabetes (types I or II), or dyslipemia * Contraindications to MRI * Contraindication to body donation Exclusion criteria * Diagnosis on MRI of brain lesions, excepted common age-related changes

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Conditions

The condition(s) this trial relates to.

nervous system disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Neurological diseases

Contacts and locations

Locations

  • Hospital of Charpennes - Lyon

    Lyon, 69000, France

  • University Hospital of Amiens

    Amiens, 80054, France

  • University Hospital of Angers

    Angers, 49033, France

  • University Hospital of Brest

    Brest, 29609, France

  • University Hospital of Nancy

    Nancy, 54511, France

  • University Hospital of Rennes

    Rennes, 35033, France

  • University Hospital of Tours

    Tours, 37044, France

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