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Brain inflammation in depression: new PET imaging study seeks answers

NCT ID NCT04582916

First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 28 times

Summary

This study uses special PET scans to see if inflammation in the brain is higher in people with major depressive disorder (MDD) during a depressive episode compared to healthy volunteers. Researchers will scan about 64 adults aged 18-70, including those with MDD and healthy controls. The goal is to understand how inflammation relates to depression, not to test a new treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.