A brain health bootcamp for seniors: could group classes ward off dementia?
NCT ID NCT05529706
First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time
Summary
This trial tests a 12-week group program designed to help adults aged 65 and older address modifiable risk factors for dementia, such as high blood pressure and cognitive decline. Participants meet weekly for an hour to learn about brain health and practice evidence-based lifestyle changes. The study aims to see if the program is acceptable, feasible, and shows early promise before moving to a larger trial.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- a 12-week group-based brain health program covering dementia risk factors and behavior change
- What this could lead to
- If successful, this program could offer a scalable, community-based approach to reduce dementia risk in older adults.
- What could go wrong
- This is a small early-stage study focused on feasibility, not proof of effectiveness. Results may not translate to larger populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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86 people
The number who actually took part.
- Started
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Apr 2023
- Finished
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Oct 2024
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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65 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Participants who are 65 years of age or older. 2. Participants who meet criteria for one or more ADRD dementia risk factors 1. Family history of Alzheimer's dementia (1st degree relative) 2. Genetic marker (APOE4++) 3. Subjective or objective cognitive decline (neuropsychological testing; or self-reported "yes" to the following question: "In the past two years, have you experienced a decline in your memory or thinking?" 4. Poorly controlled hypertension or diabetes 5. Physical inactivity \<150min/week per Surgeon General guidelines 6. Social isolation, in which participant rarely or never gets social and emotional support when needed 3. Participants who are fluent English or Spanish speakers, per self-report, to ensure reasonable neuropsychological results on key assessments. 4. Participants have access to an internet accessible device (eg. laptop, desktop computer, tablet or smartphone) 5. Participants are able to attend all 12 classes (once a week for 12 weeks) and make up missed classes, as needed 6. Participants are able to travel to/from YMCA location, if they choose to be a part of the in-person group Exclusion Criteria: 1. Inability to provide informed consent 2. Cognitive Abilities Screening Instrument - Short (CASI-Short) scores ≤ 25 (suggestive of cognitive impairment) 3. Participants with untreated psychiatric conditions, including substance abuse/dependence disorders. 4. Participants enrolled in a concurrent clinical trial involving an investigational pharmaceutical, nutraceutical, medical device, or behavioral treatment that could affect the outcome of this study. However, participation in standard treatments (e.g., occupational therapy) or use of prescribed medications (e.g., anti-depressants) is allowable. 5. Participants presently attending classes or courses like this program that is focused on dementia risk and behavior management.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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YMCA of San Francisco
San Francisco, California, 94105, United States
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