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Carotid surgery patients show brain changes – but do they recover?

NCT ID NCT00597883

Knowledge-focused Sponsor: Columbia University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how well people think and remember after surgery to clear a blocked neck artery (carotid endarterectomy). About 800 patients took brain tests before and after surgery, and their results were compared to people having spine surgery. The goal was to find out how often brain function changes happen and how long they last.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

817 people

The number who actually took part.

Start date

Mar 2003

Finished

Oct 2014

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Columbia University/NY Presbyterian Hospital

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * ability to speak English * undergoing carotid endarterectomy procedure * undergoing lumbar laminectomy procedure Exclusion Criteria: * history of permanent neurological impairment * Axis I psychiatric diagnosis or drug abuse

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Conditions

The condition(s) this trial relates to.

carotid artery disorder carotid stenosis stroke disorder transient ischemic attack

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Carotid artery disease Carotid artery stenosis Stroke Transient ischemic attack

Contacts and locations

Locations

  • Columbia University, Department of Anesthesiology

    New York, New York, 10032, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.