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Brain scans reveal Opioid's impact on Self-Control

NCT ID NCT03190954

First seen Nov 01, 2025 · Last updated Jun 17, 2026 · Updated 42 times

Summary

This study looked at how heavy opioid use changes dopamine, a brain chemical linked to addiction and self-control. Researchers compared people with opioid use disorder (some on medication, some not) to healthy volunteers using brain scans and thinking tests. The goal was to understand brain changes, not to test a new treatment.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

The condition(s) this trial relates to.

opiate dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.