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Brain chemical clues: opioid use and Self-Control under the scanner

NCT ID NCT03190954

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 29 times

Summary

This study looked at how heavy opioid use changes dopamine, a brain chemical that affects self-control and impulsiveness. Researchers compared adults with opioid use disorder (some on medication, some not) to healthy volunteers using brain scans and thinking tests. The goal was to understand the brain changes linked to addiction, not to test a new treatment.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.