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Brain training meets brain zaps: new study aims to strengthen aging minds

NCT ID NCT07441122

Knowledge-focused Sponsor: University of Texas at Austin Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jul 28, 2026 · Updated 5 times

Summary

This study explores whether combining a brain-computer interface with mild electrical stimulation or mindfulness can strengthen attention and memory in healthy adults and those with mild cognitive impairment. Participants will perform memory tasks while their brain activity is monitored and guided in real time. The goal is to see if these techniques can build cognitive reserve, the brain's ability to stay sharp despite aging or disease.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
transcranial electrical stimulation (tACS) and mindfulness-based meditation
What this could lead to
If successful, this could point toward a non-drug way to strengthen attention and memory in aging and mild cognitive impairment.
What could go wrong
This is an early, small study (100 participants) that measures brain signals, not clinical outcomes. It may not lead to any real-world benefit.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2026

Expected to finish

Feb 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 90 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Younger adults: * Good general health. * Normal or corrected vision. * no history of neurological/psychiatric disease * ability to read and understand English * ability to understand information and ability to give a free and informed consent Older adults: * Normal or corrected vision. * Self-reports no current diagnosis of dementia. * Ability to provide written/electronic, informed consent. Exclusion Criteria: Younger Adults: * Neurological or psychiatric diseases that could be contraindicated for tACS (e.g., personal history of epilepsy/seizure brain damage, history of fainting, bipolar disorder, schizophrenia, current substance use disorder, etc.). * Medications that elevate seizure threshold (e.g., stimulant medication, high dose bupropion). * Factors hindering EEG acquisition and tACS delivery (e.g., skin infection, wounds, dermatitis, inability to access the scalp of the participant). Older Adults: * Neurological or psychiatric diseases that could be contraindicated for tACS (e.g., personal history of epilepsy/seizure brain damage, pacemakers, history of fainting, bipolar disorder, schizophrenia, current substance use disorder, etc.). * Medications that elevate seizure threshold (e.g., stimulant medication, high dose bupropion). * Factors hindering EEG acquisition and tACS delivery (e.g., skin infection, wounds, dermatitis, inability to access the scalp of the participant). * Diagnosis of dementia. * Do not have the capacity to provide informed consent.

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction Memory Disorders

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Mild cognitive impairment (MCI)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Sun City

    RECRUITING

    Georgetown, Texas, 78633, United States

  • The University of Texas at Austin

    RECRUITING

    Austin, Texas, 78712, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.