Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Massive biobank aims to predict which brain aneurysms will rupture

NCT ID NCT06689410

Knowledge-focused Sponsor: Nantes University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 03, 2026 · Updated 2 times

Summary

This study is creating a large collection of medical data and biological samples from 1,100 people with brain aneurysms. The goal is to find better ways to predict which aneurysms are at risk of rupturing, which could lead to more personalized monitoring and treatment. Participants provide blood samples and imaging scans, and researchers analyze genetic and imaging features to improve risk assessment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 1,100 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2025

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria for sporadic ICA cases: * Any adult patient consulting for a definite and typical bifurcation AIC authenticated on MRI and/or cerebral arteriography * Aneurysm discovered less than a year ago, with initial imaging (MRI and/or CTA and DSA) available * Written consent obtained for study participation * Patient covered by a social security plan Inclusion criteria for index and related cases (familial forms) of intracranial aneurysms (ICA): * Index case: Any adult patient consulting for a definite and typical bifurcation ICA presenting at least one other case with ICA related (child, parent, brother, sister) detected by MRI with at least one Time of Flight (TOF) sequence. * Family relatives: children, parents, brothers, sisters, of legal age, of patients with a family history of definite, typical bifurcation AIC (≥ 4 affected), Screening to be performed using MRI with at least a Time of Flight (TOF) sequence. * Written consent to participate in the study * Patient and relatives covered by a social security plan Exclusion Criteria: * Syndromic diagnosis known to cause ICA: Marfan syndrome, OSA with SMAD 3, Elhers Danlos syndrome type II and IV, Autosomal Dominant Cystic Fibrosis, Moya-Moya syndrome * AIC with : Dissecting or fusiform, Associated with arteriovenous malformation, Blister-like, Mycotic * Cerebral white matter pathology detected on MRI evoking : Col4a1 mutation * Patient under guardianship or conservatorship * Person under court protection * Contraindication to an MRI scan

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Aneurysm are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

Aneurysm brain aneurysm Congenital, Hereditary, and Neonatal Diseases and Abnormalities

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Aneurysm Brain aneurysm Congenital disease

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    26 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • APHM

    NOT_YET_RECRUITING

    Marseille, France

  • CHRU Tours Hôpital Bretonneau

    RECRUITING

    Tours, France

  • CHRU de Nancy

    RECRUITING

    Nancy, France

  • CHU Amiens

    NOT_YET_RECRUITING

    Amiens, France

  • CHU Angers

    NOT_YET_RECRUITING

    Angers, France

  • CHU Besançon

    NOT_YET_RECRUITING

    Besançon, France

  • CHU Bordeaux Hôpital Pellegrin

    RECRUITING

    Bordeaux, France

  • CHU Caen-Normandie

    RECRUITING

    Caen, France

  • CHU Clermont-Ferrand

    RECRUITING

    Clermont-Ferrand, 63000, France

  • CHU Limoges

    NOT_YET_RECRUITING

    Limoges, France

  • CHU Rennes

    RECRUITING

    Rennes, France

  • CHU St Etienne

    NOT_YET_RECRUITING

    Saint-Etienne, France

  • CHU de Brest

    RECRUITING

    Brest, France

  • CHU de Montpellier

    NOT_YET_RECRUITING

    Montpellier, France

  • CHU de Poitiers

    NOT_YET_RECRUITING

    Poitiers, France

  • CHU de Reims

    NOT_YET_RECRUITING

    Reims, France

  • CHU de Rouen

    RECRUITING

    Rouen, France

  • CHU de Toulouse

    NOT_YET_RECRUITING

    Toulouse, France

  • GHU Paris - Hôpital Ste Anne

    RECRUITING

    Paris, France

  • HIA Sainte-Anne

    NOT_YET_RECRUITING

    Toulon, France

  • Hôpital Foch

    NOT_YET_RECRUITING

    Suresnes, France

  • Hôpital Fondation Rothschild

    NOT_YET_RECRUITING

    Paris, France

  • Hôpital La Pitié Salpêtrière

    NOT_YET_RECRUITING

    Paris, France

  • Hôpital Lariboisière

    NOT_YET_RECRUITING

    Paris, France

  • Hôpitaux Universitaires de Strasbourg

    NOT_YET_RECRUITING

    Strasbourg, France

  • Nantes University Hospital

    RECRUITING

    Nantes, Loire-Atlantique, 44093, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.