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Inside the hoarding brain: can scans reveal why letting go is so hard?

NCT ID NCT03487224

Knowledge-focused Sponsor: Stanford University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time

Summary

This study uses brain scans to explore how people with hoarding disorder make decisions compared to healthy individuals. Participants will perform cognitive tasks while undergoing fMRI, which measures brain activity by tracking blood flow. The goal is to identify differences in brain regions involved in decision-making that may contribute to hoarding behaviors.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Functional magnetic resonance imaging (fMRI) with cognitive tasks
What this could lead to
If successful, this could reveal how brain activity during decision-making differs in hoarding disorder, potentially guiding future treatments.
What could go wrong
This is a small, early-stage brain imaging study, not a treatment trial. It may not capture the full complexity of hoarding disorder or lead directly to clinical changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 25 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2018

Expected to finish

May 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Individuals with Hoarding Disorder and Healthy Participants

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Identify inclusion criteria. Inclusion criteria for participants diagnosed with HD: 1. ages 18-70 2. primary diagnosis of hoarding disorder 3. sufficient severity of hoarding symptoms 4. stable on psychotropic medications for 1 month prior to study enrollment 5. capacity to provide informed consent 6. ability to tolerate clinical study procedures Inclusion criteria for healthy control participants: 1. ages 18-70 2. capacity to provide informed consent Identify exclusion criteria. Exclusion criteria for participants with HD: 1. psychiatric or medical conditions that make participation unsafe 2. pregnant or nursing females 3. concurrent use of any medications that might increase the risk of participation (e.g. drug interactions) 4. presence of metallic device or dental braces Exclusion criteria for healthy control participants: 1. any current or lifetime psychiatric diagnosis 2. current or past use of psychotropic medication 3. pregnant or nursing females 4. major medical or neurological problem 5. presence of metallic device or dental braces

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Conditions

The condition(s) this trial relates to.

Hoarding Disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hoarding disorder

Contacts and locations

Locations

  • Stanford University

    Stanford, California, 94305, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.