Researchers dig into old records to see how botox helps stroke patients
NCT ID NCT07240337
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study reviews medical records of 34 hemiplegic patients who received botulinum toxin injections for muscle spasticity between 2017 and 2020. Researchers will analyze which muscles were injected, dosages used, and how spasticity and function changed over time. No new treatments are given; the goal is to learn from past experiences to improve future care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 34 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2025
- Expected to finish
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Nov 2025
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population consists of hemiplegic patients aged 18-75 years who received botulinum toxin treatment for upper and/or lower extremity spasticity.
- Ages
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18 to 75 years
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Aged between 18 and 75 years, clinically diagnosed with hemiplegia * Received botulinum toxin injection for upper and/or lower extremity spasticity * Availability of recorded data for two time points, including the Functional Independence Measure (FIM), Brunnstrom stage, Modified Ashworth Scale (MAS), Global Spasticity Index (GSI) * Documentation of injected muscles and total administered botulinum toxin dosage Exclusion Criteria: * Missing essential data (e.g., absence of FIM, MAS, GSI, or GAS at either visit) * Major interventions during the follow-up period such as surgery or initiation of intrathecal baclofen pump therapy * Severe concomitant neurological disorders (e.g., progressive neurodegenerative diseases) that interfere with assessment
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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İstanbul Physical Medicine and Rehabilitation Research and Training Hospital
RECRUITINGIstanbul, Bahcelievler, 34147, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Could digital skills help stroke survivors rejoin community life?
- Turning play into therapy: Ride-On toys may boost arm strength in kids with hemiplegia
- Can a smart foot device retrain walking after hemiplegia?
- Electric suit aims to ease spasticity and boost balance in kids with cerebral palsy
- Which therapy restores walking after stroke? a Head-to-Head test