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New combo therapy tested for Hard-to-Treat cancers

NCT ID NCT00479128

First seen Nov 01, 2025 · Last updated Jun 12, 2026 · Updated 41 times

Summary

This early-phase study aims to find the highest safe dose of a chemotherapy combination (gemcitabine and doxorubicin) when given with the targeted drug bortezomib. It includes up to 80 adults with advanced urothelial cancer or other solid tumors that cannot be removed by surgery. The goal is to control the disease by identifying a tolerable dose for future studies.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

The condition(s) this trial relates to.

ureter cancer Urethral Neoplasms Urinary Bladder Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.