New combo therapy tested for Hard-to-Treat cancers

NCT ID NCT00479128

First seen Nov 01, 2025 · Last updated Jun 12, 2026 · Updated 41 times

Summary

This early-phase study aims to find the highest safe dose of a chemotherapy combination (gemcitabine and doxorubicin) when given with the targeted drug bortezomib. It includes up to 80 adults with advanced urothelial cancer or other solid tumors that cannot be removed by surgery. The goal is to control the disease by identifying a tolerable dose for future studies.

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Contacts and locations

Locations

  • University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.