Refresher training may extend brain benefits for veterans with mild memory issues
NCT ID NCT05770479
First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time
Summary
This study tests whether personalized 'booster' sessions of cognitive training can help older veterans with mild cognitive impairment maintain or improve their thinking and daily functioning after completing an earlier training program. The boosters are shortened refresher modules tailored to each person's everyday goals. Researchers will measure how acceptable, appropriate, and feasible the boosters are, and get an initial look at changes in cognitive and functional performance.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Motivationally-Enhanced Compensatory Cognitive Training (ME-CCT) booster modules
- What this could lead to
- If the booster sessions are acceptable and feasible, they could offer a way to help older veterans with mild cognitive impairment hold onto or even extend the benefits of earlier cognitive training, potentially improving daily functioning.
- What could go wrong
- This is a small pilot study, so results may not apply broadly. The booster sessions are brief and may not provide additional cognitive benefit, and the study primarily measures acceptability and feasibility rather than long-term outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 28 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2023
- Expected to finish
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Jun 2028
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a US federal agency other than the NIH.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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55 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Veterans aged 55 and older who are able to provide informed consent * Previous completion of the "Cognitive Rehabilitation for Older Veterans with Mild Cognitive Impairment" \[PI: Twamley, VA CSRD: I01CX001592\] study and received the ME-CCT intervention * Independently living * English-speaking: this is necessary to complete cognitive and functional testing and participate in booster development and other study procedures Exclusion Criteria: * Participation in sub-study 2 of this CDA, in which study participants assist with the design of booster intervention modules * DSM-5 criteria for current substance use disorder and has been substance abstinent for less than 30 days * History of schizophrenia, schizoaffective disorder, or other primary psychotic disorder * History of significant brain injury with loss of consciousness \>30 minutes * Auditory or visual impairments that would prevent ability to participate in booster sessions or ability to benefit from compensatory strategies
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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VA San Diego Healthcare System, San Diego, CA
San Diego, California, 92161-0002, United States
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