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Jawbone regrowth breakthrough: growth factors help rebuild bone for dental implants

NCT ID NCT07654218

First seen Jun 23, 2026 · Last updated Jun 23, 2026

Summary

This study tested a procedure to rebuild lost jawbone in 11 people with severe bone loss, so they could later get dental implants. Surgeons used a mix of the patient's own bone, cow bone mineral, and growth factors from their blood to encourage new bone growth. The results showed that the bone graft stayed stable over 12 months, allowing successful implant placement.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Faculty of Dental Medicine, University of Porto

    Porto, Portugal

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Plasma rich in growth factors (PRGF) combined with bone graft (autogenous bone and bovine bone mineral)

What this could lead to

If successful, this approach could provide a reliable way to rebuild jawbone so people with severe bone loss can get dental implants.

What could go wrong

This was a small, early study with only 11 participants and no comparison group. Results may not apply to everyone, and the procedure carries risks like infection or graft failure.

Conditions

The condition(s) this trial relates to.

Alveolar Bone Loss Atrophic Maxilla

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.