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Donor bone vs. your own bone: which works better for jaw repair?

NCT ID NCT07367464

Disease control Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests two different bone graft mixtures for rebuilding the upper jaw in people who don't have enough bone for dental implants. One group gets a mix of animal bone and donor bone, while the other gets animal bone mixed with the patient's own bone taken from the lower jaw. Researchers will use CT scans and tissue samples to see which approach leads to better bone growth and width after 6 months.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bone graft (xenograft mixed with allograft or autograft)
What this could lead to
If successful, this could offer a less invasive option for rebuilding jawbone using donor bone instead of harvesting the patient's own bone.
What could go wrong
This is a small, early-stage study with only 32 participants, so results may not apply widely. There is also a risk of graft failure or infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 32 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2024

Expected to finish

Jun 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 50 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age: 20-50 years. * Totally or partially edentulous maxillary ridges. * Patients with insufficient bone for an implant placement. * Residual alveolar width ranging from 2 to 4 mm. * Minimum of 10 mm vertical dimension to nasal floor or sinus floor. * Patients with healthy systemic condition (Medically free). * Adequate inter-arch space for placement of the implant prosthetic part. Exclusion Criteria: * Pathological lesions in the defect site. * Systemic diseases that would interfere with bone metabolism. Uncontrolled diabetic patients. * Ongoing treatment or a history of recent chemotherapy or radiotherapy. * Patient with medical condition that contraindicates surgical procedures. * Patients on medication that may interfere with healing (Corticosteroids, Bisphosphonate, Chemo/radio therapy). * Patients with vertical bone deficiency. * Patients with habits that may jeopardize the implant longevity and affect the results of the study such as alcoholism or para-functional habits.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Guided bone regeneration

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Faculty of Dentistry Cairo University

    RECRUITING

    Cairo, Egypt

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