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Could your own bone marrow help dental implants take hold?

NCT ID NCT07657026

Disease control Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 2 times

Summary

This study tests whether applying a concentrated sample of a patient's own bone marrow around zygomatic (cheekbone) dental implants can improve bone density and implant stability. Ten adults with severe upper jawbone loss will receive the treatment, and bone density will be measured with a CT scan before and six months after surgery. The goal is to see if this approach helps the implants integrate more strongly.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
autologous bone marrow aspirate concentrate
What this could lead to
If successful, this approach could improve implant stability and bone healing for people with severe jawbone loss, potentially reducing implant failure.
What could go wrong
This is a very small, early case series with only 10 participants, so results may not apply broadly. Risks include infection, pain at the bone marrow collection site, and implant failure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 10 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients over 18 years old. * Patients requiring rehabilitation with zygomatic implants in the posterior maxilla. * Patients who are willing to participate and able to provide informed consent. Exclusion Criteria: * Pregnant women. * Individuals with history of radiation therapy or other contraindications for surgery. * Patients with bone marrow diseases. * Patients with local infections at intraoral surgical site or bone marrow aspiration site. * Patients unwilling to sign the written informed consent. * Heavy smokers \>20 cigarettes per day. * Patients taking contraindicated drugs such as bisphosphonates. * Patients with sinus pathology or acute sinusitis. * Patients with malignancy or pathology of maxilla.

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Conditions

The condition(s) this trial relates to.

Atrophic Maxilla

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Severe maxillary atrophy

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Faculty of Dentistry, Cairo University , Department of Oral and Maxillofacial Surgery

    Cairo, Cairo Governate, 11562, Egypt