Dental implant breakthrough: bone barrier technique offers hope for severe bone loss cases
NCT ID NCT07415265
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a new surgical method called the Bone Barrier technique for placing dental implants immediately after tooth removal in the front upper jaw. It included 10 adults with severe bone loss on the front side of the tooth socket. The procedure uses a thin bone plate from donated human bone and a small piece of gum tissue to rebuild the missing bone and support soft tissue. Researchers aimed to see if the technique keeps the implant stable and maintains bone and gum shape over one year.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Bone barrier technique (allogenic cortical bone lamina and connective tissue graft)
- What this could lead to
- If successful, this technique could offer a reliable way to place dental implants immediately after tooth removal, even when there is significant bone loss, potentially improving outcomes and patient satisfaction.
- What could go wrong
- This is a very small study with only 10 participants and no comparison group, so results may not apply to everyone. The procedure is surgical and carries risks like infection or graft failure.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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10 people
The number who actually took part.
- Started
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Apr 2021
- Finished
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Jan 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients who received IIP with the BB technique at the Department of Oral and Maxillofacial Implantology of Shanghai Ninth People's Hospital from April 2021 to October 2023 were included. All participants provided written informed consent prior to surgical intervention.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: (1) Presence of a non-restorable anterior tooth (canine to canine) due to severe trauma, root fracture, or endodontic failure, with healthy and natural adjacent teeth. (2) With an intact buccal gingival profile. (3) Presence of a severe buccal bone dehiscence defined as a vertical defect height of \>5 mm following extraction. (4) Sufficient residual native bone volume (≥4 mm apical to the root apex) to ensure primary implant stability. Exclusion Criteria: (1) Uncontrolled systemic diseases (e.g., diabetes mellitus, hypertension and coronary heart disease), untreated periodontitis, acute or active infection around the surgical site, or any other conditions contraindicating oral surgery. (2) Heavy smoking habits (\>10 cigarettes per day). (3) Parafunctional habits (e.g., severe bruxism). (4) Lack of compliance.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Department of Oral Maxillofacial Implantology Shanghai Ninth People's Hospital
Shanghai, Shanghai Municipality, 200010, China