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New drug combo targets cancers missing a key gene

NCT ID NCT07594626

First seen May 19, 2026 · Last updated Jun 11, 2026 · Updated 5 times

Summary

This study tests a new drug combination (BMS-986504 plus pemetrexed) in people with advanced solid tumors that have spread and are missing a gene called MTAP. The goal is to see if the combo is safe and can shrink or control the cancer. About 72 adults with certain digestive or other cancers will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Northwestern University

    Chicago, Illinois, 60611, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

The condition(s) this trial relates to.

biliary tract cancer colonic neoplasm digestive system neoplasm Esophageal Neoplasms malignant pancreatic neoplasm Neoplasm Metastasis pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.