Can fruit juice concentrates head off diabetes and heart disease?
NCT ID NCT07815847
First seen Sep 11, 2026 · Last updated Sep 11, 2026
Summary
Researchers at the University of Central Lancashire are testing whether daily blueberry or tart cherry juice concentrate can improve blood pressure and other metabolic measures in adults with pre-metabolic syndrome. Thirty people aged 18 to 65 who have two signs of metabolic syndrome, such as slightly high blood pressure or blood sugar, will take either a fruit juice concentrate or a taste-matched placebo twice a day. The study compares the two juices directly to see which, if either, helps before diabetes or heart disease develops.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- blueberry and tart cherry juice concentrates
- What this could lead to
- If the juices help, this could point toward a low-risk dietary way to slow the slide from pre-metabolic syndrome toward diabetes and heart disease.
- What could go wrong
- This is a small, short study of 30 people, so any changes may be modest or fade. Juice supplements can also add sugar to the diet, and results in this group may not apply to everyone.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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30 people
The number who actually took part.
- Started
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May 2021
- Finished
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Sep 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Aged 18-65 years. Meet two of the five metabolic syndrome criteria. Not taking prescribed medication specifically intended to manage blood pressure, blood glucose or blood lipids. Able to complete written questionnaires independently. Able to provide informed consent. Exclusion Criteria: Diagnosed diabetes mellitus. Known cardiovascular disease or clinically significant cardiovascular comorbidity, including coronary heart disease, symptomatic heart failure, clinically significant arrhythmia, or a history of stroke or transient ischaemic attack within the previous six months. Known or suspected secondary hypertension, including renal, renovascular or endocrine causes. Known clinically significant renal impairment or severe hepatic disease. Evidence or history of hypertension-related target-organ damage requiring specialist management. Pregnant or lactating. Allergy or known intolerance to tart cherry/ blueberry or any ingredient contained in the intervention or placebo. Habitual consumption of tart cherry/ blueberry products. Regular consumption of antioxidant or other dietary supplements likely to influence cardiometabolic outcomes. Body mass index greater than 40.0 kg/m². Current enrolment in another clinical trial or use of another intervention or therapy likely to influence the study outcomes. Any condition likely to compromise informed consent, protocol compliance or outcome assessment, including severe psychiatric illness, cognitive impairment, or active substance or alcohol misuse.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Central Lancashire
Preston, United Kingdom
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