Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Blood thinner safety during polyp removal put to the test

NCT ID NCT07185295

Disease control Sponsor: Outcomes'10 Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether it's safe to continue taking blood-thinning medication during the removal of colon polyps. About 481 adults on blood thinners will be randomly assigned to either keep taking their medication or stop temporarily before the procedure. Researchers will track serious bleeding within 30 days to see which approach is safer.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
anticoagulant therapy (blood thinners)
What this could lead to
If successful, this could show that continuing blood thinners during polyp removal is safe, reducing the risk of blood clots and strokes for patients.
What could go wrong
This is a phase 4 trial, but results may not apply to all patients, and there is still a risk of bleeding or other complications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

About 481 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2024

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

A research network

The lead sponsor is a research network or cooperative group.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age over 18 years. * Patients scheduled for elective outpatient colonoscopy for any indication, in whom removal of colorectal polyps will be performed if identified during the procedure. * Anticoagulant treatment with vitamin K antagonists (acenocoumarol or warfarin) or direct oral anticoagulants (dabigatran, edoxaban, apixaban, or rivaroxaban) prior to the colonoscopy. Exclusion Criteria: * Concomitant antiplatelet therapy. Age over 85 years. Urgent colonoscopy. Labile INR (time in therapeutic range less than 60%) documented in the previous 3 months in patients receiving VKAs. Supratherapeutic INR (\>3.5) at the time of the procedure in patients on VKAs. Pregnancy. Decompensated liver cirrhosis. Inability, at the investigator's discretion, to understand the periprocedural anticoagulation regimen. Known coagulopathy or bleeding diathesis, including platelet count \<50,000/µl in the previous 12 months. Scheduled endoscopic dilation. Severe psychiatric disorder. Removal of colorectal lesions by endoscopic submucosal dissection. Previous diagnosis of renal failure defined as creatinine \>2 mg/dl or clearance \<30 ml/min. Planned high bleeding risk procedure during simultaneous gastroscopy. Previous inclusion in the trial. Patients may only be included once. Patients who are not candidates for a second endoscopic intervention due to clinical conditions. Any clinical situation or concomitant treatment that, in the investigator's opinion, poses a significant bleeding risk. Patients with polyps larger than 4 cm pending endoscopic resection.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Anticoagulated patients are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

Hemorrhage

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anticoagulated patients

Contacts and locations

Locations

  • Clínica Rotger Quirónsalud

    Palma, Balearic Islands, 07012, Spain

  • Hospital Clinic de Barcelona

    Barcelona, Catalonia, 08036, Spain

  • Hospital Universitario Ramón y Cajal

    Madrid, Madrid, Spain

  • Servicio de Aparato Digestivo. Hospital Sierrallana. Barrio Ganzo,

    Torrelavega, Cantabria, 39300, Spain

  • Servicio de Aparato Digestivo. Hospital Universitario de Cabueñes

    Oviedo, Principality of Asturias, 33011, Spain

  • Servicio de Digestología, Hospital del Mar. Instituto Hospital del Mar de Investigaciones Médicas.

    Barcelona, Catalonia, 08003, Spain

  • Servicio de Gastroenterología y Hepatología. Hospital Universitario Río Hortega.

    Valladolid, Castille and León, 47012, Spain

  • Servicio de Gastroenterología y Hepatología. Hospital Universitario San Agustín.

    Avilés, Principality of Asturias, 33401, Spain

  • Servicio de Gastroenterología y Hepatología. Unidad de Endoscopias. Hospital Universitario Puerta De Hierro.

    Majadahonda, Madrid, 28222, Spain

  • Servicio de Gastroenterología. Hospital Universitario Príncipe de Asturias. Madrid.

    Alcalá de Henares, Madrid, 28805, Spain