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AI-Powered blood test could spot colon cancer before it spreads

NCT ID NCT06889883

Diagnosis Sponsor: ADVANCED MARKER DISCOVERY S.L. Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to create a blood test that can detect colorectal cancer and advanced polyps early. Researchers will use artificial intelligence to combine molecular markers and personal risk factors. The test will be developed and validated in 510 adults undergoing colonoscopy or surgery. If successful, it could offer a less invasive screening option.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 510 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2023

Expected to finish

Dec 2025

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

This study involves the recruitment of 510 patients as part of a case-control study. Patients who are going to undergo colonoscopy or who are going to undergo surgery for resection of a CRC already diagnosed will be included. They can be symptomatic or asymptomatic, ambulatory, hospitalized or consecutive patients in the Endoscopy Unit.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients over the age of 18 who are able to understand the participant information and sign the informed consent. * Patients who are going to undergo colonoscopy or surgical resection for tumor (CRC). Exclusion Criteria: * Patients who had developed any type of cancer in the 5 years prior to their participation in this study. * Patients who have received previous chemotherapy or radiotherapy. * Patients diagnosed with non-advanced adenomas, serrated polyps, Familial Adenomatous Polyposis or Lynch Syndrome. * Patients with inadequate bowel preparation for colonoscopy. * Patients who have undergone colonoscopy/polipectomy in the previous 5 years. * Patients with hemolyzed plasma.

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Conditions

The condition(s) this trial relates to.

colorectal adenoma colorectal cancer colorectal carcinoma colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Advanced adenomas (AA) Colorectal carcinoma

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    4 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Hospital Centro Médico de Asturias

    RECRUITING

    Oviedo, Principality of Asturias, Spain

  • Hospital Clinico Universitario Lozano Blesa

    RECRUITING

    Zaragoza, Aragon, Spain

  • Hospital Sant Rafael

    COMPLETED

    Barcelona, Catalonia, Spain

  • Hospital Universitario Marques de Valdecilla

    TERMINATED

    Santander, Cantabria, Spain

  • Hospital Universitario Vall d' Hebron

    COMPLETED

    Barcelona, Catalonia, Spain

  • Hospital Universitario de Cruces

    RECRUITING

    Bilbao, Basque Country, Spain

  • Hospital Universitario de Salamanca

    RECRUITING

    Salamanca, Castille and León, Spain

  • MD Anderson Cancer Centre

    ACTIVE_NOT_RECRUITING

    Madrid, Madrid, Spain

  • Policlinica Gipuzkoa Hospital

    COMPLETED

    Donostia / San Sebastian, Basque Country, Spain

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