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Artificial blood could save trauma victims when banked blood is scarce
NCT ID NCT05756426
First seen Jun 27, 2026 · Last updated Aug 26, 2026 · Updated 2 times
Summary
This study aims to create a whole blood substitute by combining artificial oxygen carriers, plasma, and platelets. Researchers will test these mixtures in the lab using blood from 250 healthy volunteers to see if they can match the performance of real blood. The goal is to have a product that can be used in emergencies, like on battlefields or in remote areas, where banked blood is not available.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- artificial blood components (oxygen carrier, plasma analogue, platelet analogue)
- What this could lead to
- If successful, this could lead to a field-ready blood substitute that saves lives in trauma situations where real blood is not available.
- What could go wrong
- This is an early laboratory study with healthy volunteers donating blood for testing, not a treatment trial. The artificial blood may not work as well as real blood or could have unexpected side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
About 250 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Apr 2023
- Expected to finish
-
Jan 2029
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
This research study intends to enroll 50healthy volunteer subjects/year over the next 5 years (total of 250 subjects).
- Ages
-
18 to 88 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Subject \>/= 18 years of age * Subject weighs \>40kg (88lbs) * Subject must be generally healthy Exclusion Criteria: * Suspected or diagnosed with ongoing (chronic) or acute infection * Subject is pregnant * Subject is non-english speaking
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Maryland Baltimore (UMB)
Baltimore, Maryland, 21201, United States
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