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New study tests cheaper vs. fancier care for high blood pressure in HIV patients

NCT ID NCT05609513

Disease control Sponsor: Infectious Diseases Research Collaboration, Uganda Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jul 24, 2026 · Updated 3 times

Summary

This study looked at two strategies to help Ugandans living with HIV and high blood pressure get better care. One strategy provided free blood pressure medicines and equipment, while the other added extra staff and support. Over 87,000 patients took part. The goal was to see which approach works best to control blood pressure and is worth the cost.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
amlodipine, valsartan, hydrochlorothiazide
What this could lead to
If successful, this could show a cost-effective way to manage high blood pressure in people with HIV in Uganda, potentially saving lives.
What could go wrong
This is an implementation study, not a test of new drugs. Results may not apply to other countries or populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

87,421 people

The number who actually took part.

Started

Feb 2023

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1\) All patients over 18 years of age receiving care at participating HIV clinics will contribute data for the effectiveness outcomes Exclusion Criteria: 1\) Patients who are not diagnosed with HIV receiving care at participating HIV clinics and are under the age of 18.

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Conditions

The condition(s) this trial relates to.

AIDS HIV infectious disease hypertensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV/AIDS Hypertension

Contacts and locations

Locations

  • Butabika

    Kampala, Uganda

  • Bweyogerere

    Wakiso, Uganda

  • Entebbe RRH

    Wakiso, Uganda

  • Kakiri

    Wakiso, Uganda

  • Kawala

    Kampala, Uganda

  • Kawanda

    Wakiso, Uganda

  • Kisenyi

    Kampala, Uganda

  • Kitebi

    Kampala, Uganda

  • Komamboga

    Kampala, Uganda

  • Mengo Hospital

    Kampala, Uganda

  • Naguru

    Kampala, Uganda

  • Nakawuka HCIII

    Wakiso, Uganda

  • Nsambya

    Kampala, Uganda

  • Nsangi HCIII

    Wakiso, Uganda

  • Nurture Africa

    Wakiso, Uganda

  • Saidina

    Wakiso, Uganda

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