Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Can a cuff ease knee pain? new study tests blood flow restriction

NCT ID NCT06637124

Symptom relief Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two types of blood flow restriction therapy (using a cuff to limit blood flow during exercise) against standard moderate strength training in 75 people with knee osteoarthritis. Participants will do supervised exercises twice a week for 8 weeks. The goal is to see which approach best reduces pain and improves muscle strength and daily function.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Blood flow restriction therapy device (Smart Cuffs 4.0)
What this could lead to
If it works, this could offer a new exercise option that reduces knee pain and improves strength without heavy weights.
What could go wrong
This is a small, early-stage trial with only 75 people. Results may not apply to everyone, and the therapy may not be better than standard exercises.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 75 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2024

Expected to finish

May 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients diagnosed with chronic knee osteoarthritis referred by orthopedic surgeons participants of both genders age are 40-65. * Patients with grade 2 and 3 OA of the knee, according to radiologic evaluation * If both knees diagnosed as OA, the most affected one will be selected. * Diagnosis of Knee OA who had knee pain and functional disabilities for at least three months, according to American College of Rheumatology classification at screening visit. * Visual Analogue Scale (VAS) at rest score of ≥40 mm. * Arabic version of the western WOMAC (ArWOMAC) scores (average 37). * Moderate Physical activity score on the IPAQ (between 3.0 and 7.9 METS). Exclusion Criteria: * Moderate to significant knee synovitis * Hot or red knee * History and/or physical examination findings compatible with the internal derangement of knee. * Knee pain that is initiated or increased with knee activity/exercise and finished or decreased with knee resting. * Other muscular, articular, or neurological condition affecting lower limb function. * Patients with any previous knee surgeries or fractures of lower limb * Patients who had undergone arthroscopy or treatment with intra-articular hyaluronic acid during the previous 6 months. * Psychological or psychiatric disorders that may affect a subject's participation in the study. * Participants with congenital musculoskeletal lower limb deformity. * Participated in other intervention studies on the past 6 months to screening * Participants with contraindications to blood flow Restriction Training.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Blood flow restriction therapy are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Blood flow restriction therapy Knee osteoarthritis

Contacts and locations

Locations

  • CairoU

    Cairo, Giza Governorate, 12611, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.