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New clotting drug may stop bleeding faster in heart surgery patients

NCT ID NCT07094087

First seen Feb 01, 2026 · Last updated May 23, 2026 · Updated 13 times

Summary

This study tests a new medicine (BE1116) against standard fresh frozen plasma to control bleeding in 200 adults during complex heart surgery with a heart-lung machine. The goal is to see if BE1116 corrects clotting problems more effectively. Participants are randomly assigned to receive either the new drug or plasma, and their blood clotting is measured 30 minutes after treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hospital Civil de Guadalajara

    NOT_YET_RECRUITING

    Guadalajara, Jalisco, 44100, Mexico

  • Kingston Health Science Center

    NOT_YET_RECRUITING

    Kingston, Ontario, K7L 2V7, Canada

  • Kyushu University Hospital

    RECRUITING

    Fukuoka, Fukuoka, 812-8582, Japan

  • London Health Sciences Center - University Campus

    RECRUITING

    London, Ontario, N6A 5A5, Canada

  • National Cerebral and Cardiovascular Center

    NOT_YET_RECRUITING

    Suita, Osaka, 564-8565, Japan

  • North Shore University Hospital

    NOT_YET_RECRUITING

    Manhasset, New York, 11040, United States

  • OUHSC (University of Oklahoma Health Sciences Center)

    RECRUITING

    Oklahoma City, Oklahoma, 73104, United States

  • Oregon Health & Sciences University

    RECRUITING

    Portland, Oregon, 97239, United States

  • Sakakibara Heart Institute

    NOT_YET_RECRUITING

    Fuchu-shi, Tokyo, 183-0003, Japan

  • Thomas Jefferson University Hospital

    RECRUITING

    Philadelphia, Pennsylvania, 19107, United States

  • UCLA Health - Ronald Reagan Medical Center

    RECRUITING

    Los Angeles, California, 90095, United States

  • UT Southwestern Medical Center

    NOT_YET_RECRUITING

    Dallas, Texas, 75390, United States

  • Universite de Montreal-Institut de Cardiologie de Montreal (ICM) Montreal Heart Institute (MHI)

    NOT_YET_RECRUITING

    Montreal, Quebec, H1T1C8, Canada

  • University of Chicago Medicine

    NOT_YET_RECRUITING

    Chicago, Illinois, 60637, United States

  • University of Cincinnati

    RECRUITING

    Cincinnati, Ohio, 45267, United States

  • University of Maryland Medical Center (UMMC)

    RECRUITING

    Baltimore, Maryland, 21201, United States

  • University of Toronto - St. Michael's Hospital (SMH) - Keenan Research Centre for Biomedical Science

    NOT_YET_RECRUITING

    Toronto, Ontario, M5B 1W8, Canada

  • University of Virginia Health System

    NOT_YET_RECRUITING

    Charlottesville, Virginia, 22908, United States

Conditions

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