New clotting drug may reduce bleeding in High-Risk heart surgeries

NCT ID NCT07094087

First seen Feb 01, 2026 · Last updated May 14, 2026 · Updated 10 times

Summary

This study tests a new medicine (BE1116) to control bleeding in 200 adults undergoing complex heart surgery with a heart-lung machine. The medicine is compared to standard fresh frozen plasma. The goal is to see if BE1116 corrects clotting problems faster and reduces the need for additional blood products.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hospital Civil de Guadalajara

    NOT_YET_RECRUITING

    Guadalajara, Jalisco, 44100, Mexico

  • Kingston Health Science Center

    NOT_YET_RECRUITING

    Kingston, Ontario, K7L 2V7, Canada

  • Kyushu University Hospital

    RECRUITING

    Fukuoka, Fukuoka, 812-8582, Japan

  • London Health Sciences Center - University Campus

    RECRUITING

    London, Ontario, N6A 5A5, Canada

  • National Cerebral and Cardiovascular Center

    NOT_YET_RECRUITING

    Suita, Osaka, 564-8565, Japan

  • North Shore University Hospital

    NOT_YET_RECRUITING

    Manhasset, New York, 11040, United States

  • OUHSC (University of Oklahoma Health Sciences Center)

    RECRUITING

    Oklahoma City, Oklahoma, 73104, United States

  • Oregon Health & Sciences University

    RECRUITING

    Portland, Oregon, 97239, United States

  • Sakakibara Heart Institute

    NOT_YET_RECRUITING

    Fuchu-shi, Tokyo, 183-0003, Japan

  • Thomas Jefferson University Hospital

    RECRUITING

    Philadelphia, Pennsylvania, 19107, United States

  • UCLA Health - Ronald Reagan Medical Center

    RECRUITING

    Los Angeles, California, 90095, United States

  • UT Southwestern Medical Center

    NOT_YET_RECRUITING

    Dallas, Texas, 75390, United States

  • Universite de Montreal-Institut de Cardiologie de Montreal (ICM) Montreal Heart Institute (MHI)

    NOT_YET_RECRUITING

    Montreal, Quebec, H1T1C8, Canada

  • University of Chicago Medicine

    NOT_YET_RECRUITING

    Chicago, Illinois, 60637, United States

  • University of Cincinnati

    RECRUITING

    Cincinnati, Ohio, 45267, United States

  • University of Maryland Medical Center (UMMC)

    RECRUITING

    Baltimore, Maryland, 21201, United States

  • University of Toronto - St. Michael's Hospital (SMH) - Keenan Research Centre for Biomedical Science

    NOT_YET_RECRUITING

    Toronto, Ontario, M5B 1W8, Canada

  • University of Virginia Health System

    NOT_YET_RECRUITING

    Charlottesville, Virginia, 22908, United States

Conditions

Explore the condition pages connected to this study.