Blood test aimed to speed up Alzheimer's diagnosis, but study was canceled
NCT ID NCT06856681
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study planned to see if using a special blood test (PrecivityAD2) could help doctors diagnose Alzheimer's disease or other dementias more quickly. It was designed for veterans and people in other closed healthcare systems who had memory problems. However, the study was withdrawn before any participants were enrolled, so no results are available.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Expected to start
-
Jul 2025
An estimate. Start dates often move.
- Expected to finish
-
Mar 2028
An estimate. End dates often move.
- Lead sponsor
-
A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
50 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Minimum age: 50 years. 2. Patients presenting with symptoms of mild cognitive impairment (MCI) or other cognitive impairments in which the enrolling clinician clinically suspects Alzheimer's pathology as the primary cause of symptomatic presentation 3. Patients presenting with mixed brain pathologies including MCI/ cognitive impairments in which the investigator clinically suspects Alzheimer's pathology as the primary or contributing cause of symptomatic presentation 4. Patients are able to attend study visits and standard care visits over the period of 1 year from the date of enrollment 5. Patients are able to undergo routine phlebotomy and provide up to six (6) 10 ml tube(s) of blood for study related tests plus any additional blood necessary for standard laboratory testing at each study timepoint 6. Patients are able to undergo standard care diagnostic procedures to include MRI (or CT), amyloid PET and/or CSF biomarker testing for AD diagnosis if prescribed by investigator 7. Patients are able to provide informed consent. Or, if in the opinion of the clinician, the patient is unable to adequately understand the nature of the trial and protocol requirements, a family member or appropriate representative of the patient is present to consent, with additional assent by the patient. Exclusion Criteria 1. Patients younger than 50 years of age 2. Patients being evaluated for cognitive impairment known to be predominantly the result of a disease or condition other than AD 3. Patients previously diagnosed with AD, unless the ADELAIDE investigator has a strong clinical suspicion suggestive of an incorrect initial diagnosis upon referral 4. Patients with no cognitive impairment or clinical symptoms of AD 5. Patients desiring genetic testing for Alzheimer's disease markers without current cognitive impairment or other relevant clinical symptoms 6. Patients who are not able or not willing to undergo standard care diagnostic procedures to include MRI (or CT), amyloid PET and/or CSF biomarker testing for AD diagnosis as prescribed by investigator 7. Patients who are not able to understand the nature of the study nor the study requirements and not represented by a family member or other appropriate representative who is able to consent on behalf of the patient 8. Patients who are not able to commit to attending the required study and/or standard care visits 9. Patients who are not able to undergo routine phlebotomy or provide blood samples in the quantity required by the study protocol
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Alzheimers disease are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can two drugs together stop Alzheimer's plaques from coming back?
- Can Real-World data reveal hidden risks of an Alzheimer's drug?
- Can a new pill change the Brain's activity in early Alzheimer's?
- Can Real-World data uncover hidden risks of the Alzheimer's drug LEQEMBI?
- Could a diabetes drug tame Alzheimer's inflammation?
- Nasal spray could tame brain inflammation in early Alzheimer's