Blink test may reveal hidden dry eye clues
NCT ID NCT07499193
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how blinking behavior is linked to the stability of the tear film in adults aged 18 to 65, both with and without dry eye symptoms. Participants will answer a questionnaire, have their vision checked, and undergo non-invasive tear film measurements using an imaging device. They will also complete three types of blink tasks to see if blinking patterns differ between the two groups.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help develop better ways to diagnose or monitor dry eye by analyzing blinking patterns.
- What could go wrong
- This is an early observational study with only 60 participants, so findings may not apply broadly. It does not test any treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Mar 2026
An estimate. Start dates often move.
- Expected to finish
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Jun 2026
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Volunteer, fluent in French, willing to follow the protocol, able to read and understand the information sheet and provide free and informed consent * Covered by a social security * Aged between 18 and 65 years inclusive * Binocular near visual acuity ≤ 0.3 LogMAR (≥ 5/10) (corrective glasses accepted) Exclusion Criteria: * Employees of Essilor International, Luxottica, or GrandVision and their subsidiaries * Pregnant or breastfeeding women (Article L1121-5) * Individuals deprived of liberty by judicial or administrative decision, or hospitalized without consent under Articles L.3212-1 and L.3213-1, who do not fall under Article L.1121-8, and individuals admitted to a health or social care facility for purposes other than research * Adults unable or incapable of giving informed consent (Article L1121-8) * Participants currently in an exclusion period from another study * Participants deemed unfit to participate by the investigator for any reason that may affect subject safety or study integrity All categories of individuals particularly protected under French law are excluded from this research (Articles L1121-5 to L1121-9 of the French Public Health Code). * Use of eye drops or ophthalmic solutions within the last 2 hours * Wearing contact lenses within the last 48 hours * Reported history of severe ocular pathology such as glaucoma, retinitis pigmentosa, diabetic retinopathy, macular involvement, resulting in visual field loss or acuity loss (especially aphakia), except for dry eye (which is not an exclusion criterion) * Reported history of eye surgery or trauma to the eye or its adnexa excepted refractive surgery and cataract surgery * Reported history of eyelid abnormalities (ptosis) * Reported history of neurological deficits, including epilepsy or sensory-motor coordination disorders, vestibular or cerebellar pathology (e.g., balance disorders, nystagmus, Parkinson's disease) * Reported history of musculoskeletal disorders preventing maintenance of a fixed head position
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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EssilorLuxottica - Neuroscience & Medical Research center
Paris, 94220, France
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