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New 'Sandwich' strategy aims to boost leukemia survival without donor transplant

NCT ID NCT06507514

First seen Nov 21, 2025 · Last updated May 22, 2026 · Updated 25 times

Summary

This study tests a new treatment plan for adults with B-cell acute lymphoblastic leukemia (B-ALL) who cannot or choose not to have a donor stem cell transplant. The approach uses the drug blinatumomab before and after an autologous (self-donated) stem cell transplant to try to clear remaining cancer cells and lower the chance of relapse. The main goals are to see if this combination is safe and improves survival. Only 4 participants will be enrolled in this early-phase trial.

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Contacts and locations

Locations

  • The First Affliated Hospital of Soochow University

    RECRUITING

    Suzhou, Jiangsu, 215006, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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