Shrinking birthmarks: bleomycin injections show promise for cystic hygromas in kids
NCT ID NCT07189832
First seen Nov 01, 2025 · Last updated Jun 24, 2026 · Updated 40 times
Summary
This study tested injecting bleomycin directly into cystic hygromas (fluid-filled birthmarks) in 30 children aged 1 month to 12 years. The fluid was drained and bleomycin injected, repeated every 4 weeks until the lump shrank. Most children saw significant size reduction, with some having complete shrinkage. This offers a potential alternative to surgery.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Cairo University Specialized Pediatric Hospital (Abu EL-Reesh hospital)
Cairo, Cairo Governorate, 12613, Egypt
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
bleomycin
What this could lead to
If successful, this approach could offer a non-surgical way to shrink cystic hygromas in children, reducing the need for more invasive procedures.
What could go wrong
This is a small, completed study with no control group, so results may not apply to all patients. Bleomycin can cause side effects like skin changes or lung issues, though rare with local injection.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.