Shrinking birthmarks: bleomycin injections show promise for cystic hygromas in kids
NCT ID NCT07189832
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study tested injecting bleomycin directly into cystic hygromas (fluid-filled birthmarks) in 30 children aged 1 month to 12 years. The fluid was drained and bleomycin injected, repeated every 4 weeks until the lump shrank. Most children saw significant size reduction, with some having complete shrinkage. This offers a potential alternative to surgery.
What this could mean
Our plain-language read of the trial. This is informational only โ not medical advice or a prediction.
- Active substance
- bleomycin
- What this could lead to
- If successful, this approach could offer a non-surgical way to shrink cystic hygromas in children, reducing the need for more invasive procedures.
- What could go wrong
- This is a small, completed study with no control group, so results may not apply to all patients. Bleomycin can cause side effects like skin changes or lung issues, though rare with local injection.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Cairo University Specialized Pediatric Hospital (Abu EL-Reesh hospital)
Cairo, Cairo Governorate, 12613, Egypt
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Other studies related to the condition(s) this trial covers.