Shrinking birthmarks: bleomycin injections show promise for cystic hygromas in kids

NCT ID NCT07189832

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested injecting bleomycin directly into cystic hygromas (fluid-filled birthmarks) in 30 children aged 1 month to 12 years. The fluid was drained and bleomycin injected, repeated every 4 weeks until the lump shrank. Most children saw significant size reduction, with some having complete shrinkage. This offers a potential alternative to surgery.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
bleomycin
What this could lead to
If successful, this approach could offer a non-surgical way to shrink cystic hygromas in children, reducing the need for more invasive procedures.
What could go wrong
This is a small, completed study with no control group, so results may not apply to all patients. Bleomycin can cause side effects like skin changes or lung issues, though rare with local injection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for LYMPHATIC MALFORMATIONS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cairo University Specialized Pediatric Hospital (Abu EL-Reesh hospital)

    Cairo, Cairo Governorate, 12613, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.