Which injection works best for Children's lymphatic malformations? new trial aims to find out

NCT ID NCT07320001

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two injected drugs, bleomycin and doxycycline, to treat lymphatic malformations (abnormal fluid-filled sacs) in children under 12. About 92 kids will be randomly assigned to one treatment, and doctors will measure how much the malformation shrinks over six months, along with any side effects. The goal is to find which option is safer and more effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

bleomycin and doxycycline (injected into the malformation)

What this could lead to

If it works, this could point toward a preferred treatment for shrinking lymphatic malformations in children, reducing the need for surgery.

What could go wrong

This is a small, early-stage trial (Phase 2) with only 92 children. The treatments may cause side effects like pain, fever, or skin damage, and one drug may not prove better than the other.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Lymphatic Abnormalities lymphatic malformation lymphatic system disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

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