Scientists hunt for hidden clues in mysterious bleeding disorders
NCT ID NCT05713734
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to find specific biological patterns in people who bleed easily for unknown reasons. Researchers will measure blood clotting, clot breakdown, and clot structure in 400 participants. The goal is to better understand the condition, not to test a new treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors better diagnose and classify bleeding disorders of unknown cause.
- What could go wrong
- This is an observational study, not a treatment trial. It may not lead to any direct medical benefit for participants.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 400 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2023
- Expected to finish
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Apr 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Women and men aged 16-65 years who have been diagnosed as patients with bleeding of unknown cause Women and men aged 16-65 years without bleeding tendency
- Ages
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16 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Man with ISTH BAT\>3. If the calculated score includes a surgical bleeding, then two other items of the score should be \>0 * Woman with ISTH BAT \>5 points. If the calculated score includes a surgical or a postpartum bleeding, then two other items of the score should be \>0 Exclusion Criteria: * Ongoing pregnancy * Intake of antithrombotic treatment or non-steroidal anti-inflammatory drugs for least 10 days at time of blood collection * Intake of antifibrinolytic or blood product administration (factor concentrate, frozen fresh plasma, prothrombin complex concentrate) for least 14 days before blood collection * Active cancer (defined as cancer diagnosis within the last five years or treatment within the two last years before study inclusion) * Active autoimmune disease * Active chronic inflammatory disease * Severe liver disease (cirrhosis \> Child A) * Renal insufficiency stage 3 * Active or recent infection (within the last 30 days) * Recent hospitalization (\<3 months) * Recent surgery (\<3 months) * Recent trauma requiring medical intervention (\<3 months)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
7 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Centre Hospitalier Universitaire Vaudois
RECRUITINGLausanne, Switzerland
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Gruppo Ospedaliero Moncucco
RECRUITINGLugano, Switzerland
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Inselspital - Universitätsspital Bern
RECRUITINGBern, Switzerland
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Kantonsspital St.Gallen
RECRUITINGSankt Gallen, Switzerland
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Ospedale Regionale di Bellinzona
RECRUITINGBellinzona, Switzerland
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USZ - Universitätsspital Zürich
RECRUITINGZurich, Switzerland
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University Hospital
RECRUITINGGeneva, Switzerland
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