Can your genes predict bladder cancer? massive study aims to find out
NCT ID NCT00848289
First seen Jun 25, 2026 · Last updated Jul 17, 2026 · Updated 3 times
Summary
This study looks at how a person's genes and lifestyle choices, like smoking, affect their risk of getting bladder cancer. Researchers will compare over 6,000 people with and without bladder cancer to find patterns. The goal is to better understand who is most at risk, which could help with prevention and early detection.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could help identify people at higher risk for bladder cancer, leading to earlier detection or prevention strategies.
- What could go wrong
- This is an observational study, not a treatment trial. It may not directly lead to new therapies, and results may not apply to all populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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6,086 people
The number who actually took part.
- Started
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Feb 1998
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Any patient who have been diagnosed with bladder cancer or who is healthy is eligible to participate without regard to age, sex, or ethnicity.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Subject has a histologically confirmed diagnosis of superficial or muscle-invasive bladder cancer * Subject is a Texas resident. * Subject can understand English or a qualified translator is available for the interview. * Subjects of any age, gender, or ethnicity are eligible to participate in the study. * Subject consents to participate in the study. Exclusion Criteria: * Subject has had prior treatment with systemic chemotherapy or radiotherapy in the past 6 months. * Subject has been diagnosed with superficial or muscle-invasive bladder cancer more than twelve months ago.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Baylor College of Medicine
Houston, Texas, 77030, United States
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MD Anderson Cancer Center
Houston, Texas, 77030, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Dutch bladder cancer cohort aims to map survival and recurrence
- Can two drugs plus chemoradiation let bladder cancer patients keep their bladder?
- Lab-Grown tumor organoids could pick the right bladder chemo
- Can tumor genes decide who keeps their bladder?
- Lab-Grown tumor models could match patients to the right cancer drug
- Can heated saline during bladder surgery stop tumors from coming back?