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AI stethoscope aims to slash antibiotic overuse in children

NCT ID NCT07362433

Diagnosis Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether an AI-powered digital stethoscope can help doctors in rural Bangladesh safely reduce antibiotic use in children with respiratory infections. About 2,500 children will be randomly assigned to standard care or care guided by the AI stethoscope. The goal is to see if the AI tool can cut antibiotic prescriptions by half without increasing treatment failures.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
AI-enabled digital stethoscope
What this could lead to
If successful, this could provide a safe, low-cost way to cut unnecessary antibiotic use in children, helping fight antibiotic resistance worldwide.
What could go wrong
This is a single trial in rural Bangladesh; results may not apply elsewhere. The AI tool might not reduce antibiotics as hoped, or could miss some infections.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

About 2,500 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2026

Expected to finish

Jun 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

2 to 59 months

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 2 to 59 months of age (60 days to 59 months 29 days), * illness duration 14 days or less, * meeting non-severe pneumonia criteria, and * from the trial catchment areas. Exclusion Criteria: * prior participation, * age \<2 months or \>59 months, * illness duration \>14 days, * not meeting IMCI-defined non-severe pneumonia criteria, * oxygen saturation (SpO2) \<90%, * moderate or severe malnutrition, * known chronic disease, * history of prematurity, * one or more high risk clinical signs (any WHO-defined clinical danger sign and/or WHO-defined emergency sign), * known antibiotic exposure in the past 1 week, * non-respiratory illness requiring systemic antibiotic treatment according to IMCI guidelines.

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Conditions

The condition(s) this trial relates to.

pneumonia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Respiratory infections in children

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Projahnnmo Research Foundation

    RECRUITING

    Sylhet, Bangladesh

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