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Herbal combo shows promise for diabetes control in small study

NCT ID NCT07303127

Disease control Sponsor: Universitas Muhammadiyah Surakarta Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a daily supplement of bitter melon extract and snakehead fish powder could help lower blood sugar in adults with type 2 diabetes. Eighty participants took either the supplement or a placebo for four weeks while continuing their usual metformin medication. Researchers measured changes in fasting blood sugar and other markers to see if the combination offers any benefit.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bitter melon extract and snakehead fish powder
What this could lead to
If it works, this could point toward a natural supplement to help manage blood sugar in type 2 diabetes alongside standard medication.
What could go wrong
This is a small, early pilot study with only 80 participants over 4 weeks. Results may not apply to everyone, and the supplement may not significantly lower blood sugar.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

80 people

The number who actually took part.

Started

Jun 2021

Finished

Oct 2021

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

25 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosed with Type 2 Diabetes Mellitus (T2DM). * Age 25-65 years. * Currently treated with one type of biguanide (metformin). * Fasting plasma glucose 126-200 mg/dL. * Willing to participate and sign informed consent. * Able to attend all study visits at participating health centers. Exclusion Criteria: * Positive pregnancy test or currently breastfeeding. * Impaired renal function (creatinine \> 1.5 mg/dL). * Impaired liver function (SGOT \> 40 U/L or SGPT \> 35 U/L, or ≥2× upper normal limit). * Known allergy to bitter melon extract or snakehead fish powder. * Any condition judged by investigators to interfere with study participation. * Participants who withdraw consent or are unable to complete the intervention.

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Conditions

The condition(s) this trial relates to.

type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Type 2 diabetes mellitus (T2DM)

Contacts and locations

Locations

  • Faculty of Health Sciences, Universitas Muhammadiyah Surakarta

    Surakarta, Centre Java, 57162, Indonesia

More trials for these conditions

Other studies related to the condition(s) this trial covers.