Major study pits four bipolar depression drugs Head-to-Head
NCT ID NCT06433635
First seen Jan 06, 2026 · Last updated May 22, 2026 · Updated 17 times
Summary
This study compares four commonly prescribed medications for bipolar depression in over 2,700 adults. Participants receive one of three FDA-approved drugs or a combination therapy. The goal is to see which treatment leads to remission, meaning fewer depressive symptoms and better overall well-being. This is a phase 4 trial, meaning the drugs are already approved and being tested in real-world settings.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Case Western Reserve University
Cleveland, Ohio, 44106-1712, United States
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John Hopkins
Baltimore, Maryland, 21218, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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McLean Hospital
Belmont, Massachusetts, 02478, United States
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Montefiore Medical Center and Albert Einstein College of Medicine
New York, New York, 10461, United States
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Nagy Youssef
Grand Rapids, Michigan, 49548, United States
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New York University Grossman School of Medicine NYU
New York, New York, 10016, United States
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Steve Strakowski
Bloomington, Indiana, 47405, United States
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UT Health Houston Texas
Houston, Texas, 77030, United States
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UT Southwestern Medical Center
Dallas, Texas, 75390-7208, United States
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University of Alabama Birmingham
Birmingham, Alabama, 35294, United States
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University of British Columbia
Vancouver, British Columbia, V6T 1Z4, Canada
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University of Michigan
Ann Arbor, Michigan, 48109, United States
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University of New Mexico Health Sciences Center Albuquerque
Albuquerque, New Mexico, 87131-0001, United States
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University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, 27599, United States
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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University of Pittsburgh
Pittsburgh, Pennsylvania, 15260, United States
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University of Texas at Austin
Austin, Texas, 78712, United States
Conditions
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