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Can allergy drugs help kids tolerate peanut and more?

NCT ID NCT03679676

First seen Jun 08, 2026 · Last updated Jun 21, 2026 · Updated 2 times

Summary

This study tested whether adding the drugs omalizumab (Xolair) or dupilumab (Dupixent) to oral immunotherapy (OIT) helps people with multiple food allergies tolerate more allergens. 130 participants aged 4 to 55 with allergies to peanut plus one or two other foods were enrolled. The goal was to see if these biologics improve the success of passing a food challenge to peanut and other allergens.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Sean N. Parker Center for Allergy & Asthma Research at Stanford University

    Palo Alto, California, 94304, United States

  • University of California Los Angeles (UCLA)

    Los Angeles, California, 90095, United States

  • University of California San Diego (UCSD)

    San Diego, California, 92123, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

omalizumab (Xolair) and dupilumab (Dupixent)

What this could lead to

If successful, this could lead to a safer and more effective way to treat multiple food allergies at once, reducing the risk of severe allergic reactions.

What could go wrong

This is a Phase 2 trial with a moderate number of participants, so results may not apply to everyone. The biologics can have side effects, and the treatment may not work for all allergens.

Conditions

The condition(s) this trial relates to.

food allergy Hypersensitivity Peanut Hypersensitivity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.