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New sock could ease pain after knee surgery

NCT ID NCT04751942

Symptom relief Sponsor: University Hospitals Cleveland Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a special non-compressive bioactive garment helps people recover better than standard TED stockings after total knee replacement. Twenty-three patients wore either the new garment or the standard hose, and researchers measured pain, swelling, range of motion, and painkiller use. The goal is to find a more comfortable way to reduce pain and swelling right after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Non-compressive bioactive garment (device)
What this could lead to
If this garment works better than standard stockings, it could give people a more comfortable way to recover after knee replacement surgery with less pain and swelling.
What could go wrong
This is a very small, early study with only 23 participants, so results may not apply to everyone. The garment might not prove better than the current standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

23 people

The number who actually took part.

Started

Oct 2023

Finished

Jan 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 89 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Primary unilateral Total Knee Replacement - Cruciate retaining and Posterior stabilized designs Exclusion Criteria: * Leg circumference \> 23 in. * Allergy to silicone/polyester * Current DVT * Primary Inflammatory Type arthritis (i.e. rheumatoid arthritis) * Inability to follow standardized post op and rehab protocols * Lymphedema * History of Vascular Bypass Surgery on Operative Limb (i.e. Fem-Pop or Fem-Fem) * Chronic Narcotic Use History

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Conditions

The condition(s) this trial relates to.

osteoarthritis susceptibility 6 osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Osteoarthritis knees both

Contacts and locations

Locations

  • University Hospitals Beachwood Medical Center

    Beachwood, Ohio, 44122, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.