Can a second brain zap tame tremors on both sides?
NCT ID NCT06974916
First seen Jan 07, 2026 · Last updated Jun 20, 2026 · Updated 18 times
Summary
This study tests whether a second focused ultrasound treatment on the opposite side of the brain can further reduce tremors in people with essential tremor who already had one treatment. About 100 participants will be randomly assigned to get the second procedure or continue standard care. The main goal is to see if tremor scores improve more in the treated group after 6 months.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Ascires Hospital_ECG Salud
ACTIVE_NOT_RECRUITINGValencia, 46014, Spain
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Clinica Universidad de Navarra
RECRUITINGPamplona, 31008, Spain
Contact Email: •••••@•••••
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Fondazione IRCCS Istituto Neurologico Carlo Besta
RECRUITINGMilan, 20133, Italy
Contact Email: •••••@•••••
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Germans Trias i Pujol Hospital
RECRUITINGBadalona, 08916, Spain
Contact Email: •••••@•••••
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HM CINAC- Hospital Universitario HM Puerta del Sur
RECRUITINGMóstoles, 28938, Spain
Contact Email: •••••@•••••
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The Walton Center
NOT_YET_RECRUITINGLiverpool, L97LJ, United Kingdom
Contact Email: •••••@•••••
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Turku University Hospital
RECRUITINGTurku, FI20520, Finland
Contact Email: •••••@•••••
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Universitätsklinikum Schleswig-Holstein, Campus Kiel (UKSH)
RECRUITINGKiel, 24105, Germany
Contact Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
focused ultrasound (Exablate) procedure
What this could lead to
If successful, this could offer a way to treat tremors on both sides of the body with a non-invasive procedure, potentially reducing the need for medication.
What could go wrong
This is a relatively small, early-stage study (100 people) and focused ultrasound can cause side effects like numbness or balance issues. It is not a cure, and long-term benefits are unproven.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.