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New antibody drug targets Hard-to-Treat brain tumors

NCT ID NCT05916313

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 29 times

Summary

This early-stage trial tests a new drug, BI 764532, in adults with a type of brain tumor (glioma) that has a specific marker called DLL3. The drug is designed to help the body's immune cells attack the tumor. The main goal is to find the highest dose that is safe, and to see if it can control the disease. About 18 people whose previous treatments stopped working will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Cantonal Hospital of Aarau

    Aarau, CH-5001, Switzerland

  • Erasmus Medisch Centrum-ROTTERDAM-50697

    Rotterdam, 3015 GD, Netherlands

  • Hospital Universitario 12 de Octubre

    Madrid, 28041, Spain

  • Hospital del Mar

    Barcelona, 08003, Spain

  • Klinikum der Universität München AÖR

    München, 81377, Germany

  • SCRI Oncology Partners

    Nashville, Tennessee, 37203, United States

  • Salzburg Cancer Research Institute

    Salzburg, 5020, Austria

  • University Hosp. Zurich

    Zurich, 8901, Switzerland

  • University Hospital of Lausanne

    Lausanne, 1101, Switzerland

  • University of California Irvine

    Orange, California, 92868, United States

  • Universitätsklinikum Frankfurt

    Frankfurt, 60596, Germany

  • Universitätsklinikum Tübingen

    Tübingen, 72076, Germany

Conditions

Explore the condition pages connected to this study.