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Could a blood flow cuff boost knee pain relief without heavy lifting?

NCT ID NCT07283237

Symptom relief Sponsor: Assiut University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether adding a blood flow restriction cuff to targeted exercises helps adults aged 30-55 with mild to moderate knee osteoarthritis and bow legs feel less pain and move better. About 80 participants will be randomly assigned to do exercises either with or without the cuff. Researchers will track knee function, pain, and quality of life over 12 months to see if the cuff makes a difference.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 80 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2025

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

30 to 55 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 30 and 55 years * Body Mass Index (BMI) between 18 and 25 * Presence of medial knee pain * Mild to moderate varus deformity confirmed via X-Ray Long Film (2° \< HKA ≤ 10°) (4)(4)(5) * Kellgren and Lawrence classification of osteoarthritis (grades 1-3) (6): * Grade 1 (doubtful): doubtful joint space narrowing and possible osteophytic lipping * Grade 2 (minimal): definite osteophytes and possible joint space narrowing * Grade 3 (moderate): moderate multiple osteophytes, definite narrowing of joint space, some sclerosis and possible deformity of bone ends * Active adults (based on REFA work classification) Exclusion Criteria: * BMI \> 25 * History of knee surgery * Any contraindication to exercise or BFR, including: * History of deep vein thrombosis (DVT) * Uncontrolled hypertension * Peripheral vascular disease * Pregnancy * Other significant musculoskeletal or neurological conditions affecting lower extremity function (e.g., hip osteoarthritis, rheumatoid arthritis, peripheral neuropathy)

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Knee osteoarthritis (mild to moderate, medial compartment) Medial knee pain Varus knee deformity

Contacts and locations

Locations

  • Faculty of Medicine, Assiut University

    Asyut, Asyut Governorate, Egypt