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Natural cholesterol fix? bergamot & artichoke supplement put to the test

NCT ID NCT07178769

Disease control Sponsor: Laboratoires Arkopharma Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study is testing whether a daily supplement made from bergamot, artichoke, and other natural ingredients can lower LDL (bad) cholesterol in people with mild to moderate high cholesterol. 207 participants will take either one or two capsules daily for four months, or just follow healthy lifestyle advice. The goal is to see if the supplement improves cholesterol levels more than lifestyle changes alone.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
dietary supplement containing bergamot, artichoke, and other ingredients
What this could lead to
If it works, this could offer a natural supplement option to help lower cholesterol, potentially reducing the need for medication in some people.
What could go wrong
This is an early-stage trial with no prior strong evidence for this specific supplement. The effect may be small or no better than healthy lifestyle changes alone. Dietary supplements are not as strictly regulated as drugs.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 207 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2025

Expected to finish

Jul 2026

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Patients who are willing and able to understand and sign the informed consent after the nature of the study has been fully explained to them and they have passed the inclusion/exclusion criteria. 2. Patients aged greater than or equal to 18 years 3. Patients with moderate or mild cardiovascular risk, who have LDL levels greater than 130 mg/dl. Exclusion Criteria: 1. Use of any other drug or food supplement for the treatment of hypercholesterolemia during the 30 days prior to selection. 2. Allergy or hypersensitivity to any of the components of the study treatment. 3. Decompensated cardiovascular disease, decompensated diabetes mellitus, decompensated HTN. 4. Serious medical conditions such as: cancer, serious chronic illness considered incompatible with participation in the study or others that may interfere with the study. 5. HIV-AIDS, Pregnancy or breastfeeding, occlusion of the central retinal artery (of foreseeable vascular origin), history of cardiovascular disease and familial hypercholesterolemia. 6. Liver, kidney or muscle disorders. 7. Psychiatric disorders or inability to sign the consent. 8. Subjects with extreme eating habits and/or with a significant history of anorexia nervosa, bulimia and other eating disorders.

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Conditions

The condition(s) this trial relates to.

hyperlipidemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cholesterolemia

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    7 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Centro de Salud Avenida de Aragón

    NOT_YET_RECRUITING

    Madrid, Madrid, 28027, Spain

  • Centro de Salud Avenida de Aragón

    NOT_YET_RECRUITING

    Madrid, Madrid, 28027, Spain

  • Centro de Salud Casco Antiguo

    RECRUITING

    Cartagena, Murcia, 30201, Spain

  • Centro de Salud Daroca

    RECRUITING

    Madrid, Madrid, 28017, Spain

  • Centro de Salud Goya

    NOT_YET_RECRUITING

    Madrid, Madrid, 28009, Spain

  • Centro de Salud Isaac Peral

    RECRUITING

    Cartagena, Murcia, 30300, Spain

  • Centro de Salud de Mazarrón

    RECRUITING

    Mazarrón, Murcia, 30870, Spain