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New drug cocktail aims to extend lives in tough kidney cancer

NCT ID NCT07489495

First seen Apr 16, 2026 · Last updated May 20, 2026 · Updated 6 times

Summary

This study tests whether adding a new targeted drug (zanzalintinib) to standard belzutifan therapy helps people with advanced kidney cancer live longer and keep their cancer from growing. About 758 adults whose cancer worsened after at least one prior treatment will receive either the combo or belzutifan alone. The goal is to see if the combination improves survival and delays cancer progression.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Asan Medical Center ( Site 2901)

    RECRUITING

    Seoul, 05505, South Korea

    Contact Phone: •••-•••-••••

  • Centro Oncológico Riojano Integral ( Site 0256)

    RECRUITING

    La Rioja, X5004BAL, Argentina

    Contact Phone: •••-•••-••••

  • Centro Privado de RMI Río Cuarto S.A. II ( Site 0255)

    RECRUITING

    Río Cuarto, Córdoba Province, X5800ALB, Argentina

    Contact Phone: •••-•••-••••

  • Macquarie University ( Site 2700)

    SUSPENDED

    Macquarie University, New South Wales, 2109, Australia

  • Rambam Health Care Campus ( Site 1600)

    RECRUITING

    Haifa, 3109601, Israel

    Contact Phone: •••-•••-••••

  • Samsung Medical Center ( Site 2902)

    RECRUITING

    Seoul, 06351, South Korea

    Contact Phone: •••-•••-••••

  • Severance Hospital, Yonsei University Health System ( Site 2903)

    RECRUITING

    Seoul, 03722, South Korea

    Contact Phone: •••-•••-••••

  • Sheba Medical Center ( Site 1601)

    RECRUITING

    Ramat Gan, 5265601, Israel

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.