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New drug duo targets hard-to-treat melanoma in phase 2 trial

NCT ID NCT07449754

First seen Mar 09, 2026 · Last updated May 24, 2026 · Updated 11 times

Summary

This study tests a combination of two oral drugs, belvarafenib and cobimetinib, in people with advanced or spreading NRAS-mutant melanoma who have no good standard treatment left. About 45 adults will take the pills daily in 28-day cycles to see if tumors shrink or stop growing. The goal is to measure how well the drugs work and how safe they are.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Asan Medical Center

    RECRUITING

    Seoul, 05505, South Korea

  • Chonnam National University Hwasun Hospital

    NOT_YET_RECRUITING

    Hwasun, Jeollanam-do, 58128, South Korea

  • Chungnam National University Hospital

    NOT_YET_RECRUITING

    Daejeon, 35015, South Korea

  • Dong-A University Medical Center

    RECRUITING

    Busan, 49201, South Korea

  • Korea University Guro Hospital

    NOT_YET_RECRUITING

    Seoul, 08308, South Korea

  • Kyungpook National University Chilgok Hospital

    NOT_YET_RECRUITING

    Daegu, 41404, South Korea

  • Samsung Medical Center

    RECRUITING

    Seoul, 06351, South Korea

  • Seoul National University Bundang Hospital

    NOT_YET_RECRUITING

    Seongnam-si, Gyeonggi-do, 13620, South Korea

  • Seoul National University Hospital

    NOT_YET_RECRUITING

    Seoul, 03080, South Korea

  • Severance Hospital

    RECRUITING

    Seoul, 03722, South Korea

Conditions

Explore the condition pages connected to this study.