New drug combo targets Hard-to-Treat melanoma

NCT ID NCT07449754

First seen Mar 09, 2026 · Last updated May 17, 2026 · Updated 8 times

Summary

This study tests whether combining two oral drugs, belvarafenib and cobimetinib, can shrink tumors in people with advanced melanoma that has a specific NRAS gene mutation. About 45 adults whose cancer has not responded to standard treatments will receive the drug combination for 28-day cycles. The main goal is to see how many patients experience tumor shrinkage, while also monitoring side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ADVANCED OR METASTATIC MELANOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Asan Medical Center

    RECRUITING

    Seoul, 05505, South Korea

  • Chonnam National University Hwasun Hospital

    NOT_YET_RECRUITING

    Hwasun, Jeollanam-do, 58128, South Korea

  • Chungnam National University Hospital

    NOT_YET_RECRUITING

    Daejeon, 35015, South Korea

  • Dong-A University Medical Center

    RECRUITING

    Busan, 49201, South Korea

  • Korea University Guro Hospital

    NOT_YET_RECRUITING

    Seoul, 08308, South Korea

  • Kyungpook National University Chilgok Hospital

    NOT_YET_RECRUITING

    Daegu, 41404, South Korea

  • Samsung Medical Center

    RECRUITING

    Seoul, 06351, South Korea

  • Seoul National University Bundang Hospital

    NOT_YET_RECRUITING

    Seongnam-si, Gyeonggi-do, 13620, South Korea

  • Seoul National University Hospital

    NOT_YET_RECRUITING

    Seoul, 03080, South Korea

  • Severance Hospital

    RECRUITING

    Seoul, 03722, South Korea

Conditions

Explore the condition pages connected to this study.