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New drug hope for rare immune disorder? safety trial begins

NCT ID NCT04097561

First seen Jan 05, 2026 · Last updated May 21, 2026 · Updated 22 times

Summary

This early-stage study tests whether belimumab is safe for people with idiopathic CD4 lymphopenia (ICL), a rare condition where the body has too few CD4 immune cells, raising infection risk. About 20 adults aged 18-70 with ICL and autoantibodies will receive 8 doses of belimumab through an IV over several months. The main goal is to check for side effects, while also tracking changes in immune cell counts.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.