Beetroot juice may boost heart recovery in diabetes
NCT ID NCT07560800
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study will test whether a single dose of beetroot juice can improve blood pressure and heart rate recovery after light cycling in adults with type 2 diabetes. About 20 participants aged 40-65 will receive either beetroot juice or a placebo in random order. The goal is to see if the nitrates in beetroot juice help blood vessels relax and speed up recovery after exercise.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Beetroot juice (nitrate-rich dietary supplement)
- What this could lead to
- If it works, this could point toward a simple dietary supplement to help people with type 2 diabetes manage blood pressure and recover better after exercise.
- What could go wrong
- This is a very small, early-stage trial with only 20 participants, so results may not apply widely. The effect is acute (single dose) and may not translate to long-term benefits.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 20 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Apr 2026
An estimate. Start dates often move.
- Expected to finish
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Jul 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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40 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Clinically diagnosed Type 2 Diabetes Mellitus * Aged 40 to 65 years * Not treated with insulin * Stable diabetes medication regimen for at least 3 months * Able to understand the study information and provide informed consent * Able to safely perform light-to-moderate cycling exercise Exclusion Criteria: * Current or recent use of insulin * Use of organic nitrates (e.g., glyceryl trinitrate) or phosphodiesterase-5 inhibitors (e.g., sildenafil, tadalafil) * Use of systemic antibiotics within the specified preparation period or regular use of antiseptic/antibacterial mouthwash during study participation * Use of supplements known to interfere with nitric oxide metabolism within the defined preparation period * Unstable or clinically significant cardiovascular disease * Uncontrolled hypertension or any condition that makes exercise unsafe * Chronic kidney disease, history of kidney stones, or other relevant renal conditions * Neurological, musculoskeletal or systemic disorders that impair safe participation * Known or suspected allergy or intolerance to beetroot, lemon or any component of the study products * Pregnancy or breastfeeding * Inability to comply with study preparation requirements
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Clinical Physiology Laboratory, Oxford Brookes University
Oxford, Oxfordshire, OX3 0BP, United Kingdom
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