Bee venom zaps sinus pain? new trial tests sting therapy
NCT ID NCT07151313
First seen Jun 24, 2026 · Last updated Aug 05, 2026 · Updated 3 times
Summary
This study tests whether applying bee venom to the face using ultrasound can ease chronic sinusitis symptoms. Thirty adults with sinusitis will either get bee venom phonophoresis or standard care (decongestants and saline rinses). Researchers will measure changes in symptom severity, pain, and quality of life over the treatment period.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- bee venom extract applied via ultrasound
- What this could lead to
- If it works, this could offer a new, non-drug option to reduce sinusitis symptoms like facial pain and congestion.
- What could go wrong
- This is a very small early trial with only 30 people, so results may not apply broadly. Bee venom can cause allergic reactions, and the treatment may not work better than standard care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18 to 65 years. * Clinical diagnosis of chronic sinusitis (symptoms ≥ 12 weeks) or acute sinusitis confirmed by an otolaryngologist. * Willing and able to provide written informed consent. Exclusion Criteria: * Known allergy or hypersensitivity to bee venom or bee products. * Skin conditions (e.g., eczema, dermatitis, open wounds) over the area of ultrasound application. * Severe comorbid medical conditions (e.g., uncontrolled asthma, autoimmune disease, malignancy). * Pregnancy or breastfeeding. * Use of systemic corticosteroids, antibiotics, or other medications that may significantly alter sinusitis symptoms within 4 weeks prior to enrollment. * Participation in another clinical trial within the past 30 days.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Sinai university
Cairo, 44511, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- New nasal spray aims to unblock stuffy noses fast
- Withdrawn study sought to understand sinus problems in young cancer survivors