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Lying down for 5 days: scientists watch muscles shrink in real time

NCT ID NCT07178353

Knowledge-focused Sponsor: Queen's University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 2 times

Summary

This study looks at what happens to muscle size, strength, and insulin sensitivity after 5 days of strict bedrest in healthy young adults. Twelve volunteers will undergo tests before and after the bedrest period, including MRI scans, strength tests, and muscle biopsies. The goal is to better understand how quickly muscle loss and metabolic changes occur during short-term inactivity.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 12 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2025

An estimate. Start dates often move.

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 30 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Males and females 18-30 years * BMI between 18.5-28 kg/m2 * Weight stable (within ±2kg for 6 months) * Generally healthy as assessed by medical and physical activity questionnaires * recreationally active Exclusion Criteria: * a BMI \< 18.5 and \> 28 kg/m2 * the use of insulin to control blood glucose levels * a history of any cardiovascular, respiratory, metabolic diseases, neuromuscular or bone-wasting diseases * the use of any medication that may affect muscle protein turnover (e.g. androgen or anabolic hormone therapy, chemotherapy) * a (family) history of thrombosis, platelet or coagulation disorders, or antiplatelet therapy and the use of anticoagulant medications * the presence of any unremoved, or partially removed metals underneath the skin * a history of head or eye injury involving metal fragments * have some type of implanted electrical device (such as a cardiac pacemaker or neurostimulator) * have implanted metal objects as a result of surgery, such as artificial joints, aneurysm clips, metal staples * are, or may be, pregnant * are wearing metal braces on their teeth.

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Conditions

The condition(s) this trial relates to.

Insulin Resistance muscular atrophy Muscular Disorders, Atrophic

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Insulin resistance Muscle protein synthesis Muscular atrophy

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Queen's Univeristy

    RECRUITING

    Kingston, Ontario, K7L 3N6, Canada

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