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Aspirin after brain bleed: could a common pill prevent another disaster?

NCT ID NCT07243704

Disease control Sponsor: Christian Medical College and Hospital, Ludhiana, India Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether taking a daily low-dose aspirin can reduce the risk of major heart problems and strokes in people who have survived a brain bleed (intracerebral hemorrhage). About 5,676 adults will be randomly assigned to receive either aspirin or a placebo for up to three years. The goal is to see if the benefits of preventing clots outweigh the risk of causing another bleed.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

About 5,676 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Feb 2026

An estimate. Start dates often move.

Expected to finish

Feb 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 99 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥18 years * First-ever Intracerebral Haemorrhage * Presenting ≥24 hrs up to 3 months of stroke symptoms confirmed by brain imaging * CT /MRI confirming Intracerebral Haemorrhage * Alive ≥24 hours after non-traumatic ICH Exclusion Criteria: * ICH is known to be due to trauma, a structural cause (e.g., aneurysm, arteriovenous malformation, cerebral cavernous malformation, venous thrombosis, or tumour), or haemorrhagic transformation of cerebral infarction * Glasgow coma score ≤5 * Taking any antiplatelet or anticoagulant therapy 15 days prior to randomization. * Women pregnant, breastfeeding, childbearing potential, and not using contraceptives * Enrolled in any other clinical trial * Sick or compromised patients with life expectancy of less than a year * Geographical or other factors that prohibit long-term follow-up

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Conditions

The condition(s) this trial relates to.

intracerebral hemorrhage stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Intracerebral haemorrhage

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    40 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • All India Institute of Medical Science

    Patna, Bihar, 801507, India

  • All India Institute of Medical Science

    Guwahati, 781101, India

  • All India Institute of Medical Science

    New Delhi, 110029, India

  • All India Institute of Medical Sciences

    Bilāspur, Himachal Pradesh, 174001, India

  • All India Institute of Medical Sciences

    Bhubaneswar, Odisha, 751019, India

  • All India Institute of Medical Sciences

    Raebareli, Uttar Pradesh, 229405, India

  • Amrita Institute for Medical Sciences and Research Center

    Kochi, Kerala, 682041, India

  • Apollo Excelcare Hospitals

    Guwahati, Assam, 781033, India

  • Bangur Institute of Neurosciences

    Kolkata, West Bengal, 700020, India

  • Baptist Christian Hospital

    Tezpur, Assam, 784001, India

  • Bharati Vidyapeeth DTU Medical College

    Pune, Maharashtra, 411043, India

  • Christian Medical College Vellore

    Vellore, Tamil Nadu, 632517, India

  • Dr Ramesh Cardiac and Multispecialty Hospital

    Guntur, Andhra Pradesh, 522004, India

  • Government General Hospital

    Guntur, Andhra Pradesh, 522001, India

  • Government General Hospital

    Kākināda, Andhra Pradesh, 533003, India

  • Government Medical College

    Anantnag, Jammu and Kashmir, 192101, India

  • Government Medical College Trivandrum

    Thiruvananthapuram, Kerala, 695011, India

  • Guru Gobind Singh Medical College and Hospital

    Farīdkot, Punjab, 151203, India

  • Institute of Human Behaviour and Allied Sciences

    New Delhi, National Capital Territory of Delhi, 110095, India

  • Institute of Medical Sciences of the Banaras Hindu University (BHU)

    Varanasi, Uttar Pradesh, 221005, India

  • Jaiswal Hospital and Neuro Institute

    Kota, Rajasthan, 324005, India

  • KG Hospital and Post Graduate Medical Institute Coimbatore

    Coimbatore, Tamil Nadu, 641018, India

  • KIMS-Sunshine Hospitals

    Hyderabad, 500016, India

  • KLE's Dr. Prabhakar Kore Hospital & Medical Research Centre

    Belagavi, Karnataka, 590010, India

  • Kasturba Medical College Manipal

    Manipal, Karnataka, 576104, India

  • King George's Medical University

    Lucknow, Uttar Pradesh, 226003, India

  • Lalitha Super Specialty Hospital

    Guntur, Andhra Pradesh, 522001, India

  • Manipal Group of Hospitals (Eastern Region)

    Kolkata, 700017, India

  • Narayana Medical College and Hospital

    Nellore, Andhra Pradesh, 524003, India

  • P. D. Hinduja Hospital and Medical Research Centre

    Mumbai, Maharashtra, 400016, India

  • PBM Hospital

    Bikaner, Rajasthan, 334001, India

  • Rajendra Institute of Medical Sciences

    Ranchi, Jharkhand, 834009, India

  • Renova Institute of Neurological Sciences (RINS); Renova Century Hospital

    Hyderabad, 500034, India

  • Sahyadri Superspeciality Hospital

    Nashik, Maharashtra, 422001, India

  • Sanjay Gandhi Postgraduate Institute of Medical Sciences

    Lucknow, 226014, India

  • Santokba Durlabhji Memorial Hospital

    Jaipur, Rajasthan, 302015, India

  • Shri Maharaja Hari Singh (SMHS) Hospital

    Srinagar, Jammu and Kashmir, 190010, India

  • Sree Chitra Tirunal Institute for Medical Sciences and Technology

    Thiruvananthapuram, Kerala, 695011, India

  • St Stephen's Hospital

    Delhi, 110054, India

  • Tirunelveli Medical College

    Tirunelveli, Tamil Nadu, 627011, India

More trials for these conditions

Other studies related to the condition(s) this trial covers.